Bangladesh Agricultural University (BAU)

Course Code: BMB 2205

Course Title: Biochemistry

Credit: 3 (Three)

Contact Hours: 3 Hours per week

Level: 2 Semester: 2

Course offering Department: Department of Biochemistry and Molecular Biology

Rationale:

The students need to have a proper knowledge on the physical, chemical and metabolic aspects of biomolecules for understanding physiological phenomena of fishes and fisheries, and their improvement.

Course Learning Outcomes (CLO):

Classify various biomolecules and discuss their metabolic fates.
Compare and contrast among various biomolecules and metabolic processeswith energetics.
Construct structural forms of unknown biomolecules and make relationship among the various metabolic processes.
Enrich knowledge of molecular biology and make skill to construct recombinant DNA and clones for development of new variety.

Mapping CLO with PLO

CLO/PLO	PLO1	PLO2	PLO3	PLO4	PLO5	PLO6	PLO7	PLO8	PLO9	PLO10
CLO1	××	××
CLO2	××	××	××
CLO3	××	××	××				××
CLO4	××	××	××		××		××

Summary of Course Content

Sl No.	Content	Aligned CLO	No. of Lectures
1	Introduction to Biochemistry: Scope and importance. Cell organization and biological function of different organelles. Cell signaling and role of transporters. Concept of metabolism Water and aquatic life.	CLO1	2
2	Chemistry and Metabolism of Carbohydrates: Classification, biological function and structural features. Cell wall polysaccharides. Glycolysis. Fermentation. Shuttle system. TCA Cycle. Electron Transport Chain. Hexose Monophosphate Shunt and Gluconeogenesis.	CLO1, CLO2 & CLO3	9
3	Chemistry and Metabolism of Proteins: Classification and function of amino acids and proteins. Reactions in protein chemistry. Nutritive value of fish protein concentrate. Food protein quality evaluation. Chemistry of antifreezing active principle in polar aquatic animal. Organization levels. Denaturation. Basic processes of amino acid catabolism. Nitrogen excretory products in aquatic animals. Fixation of nitrogen by aquatic plants.	CLO1, CLO2 & CLO3	10
4	Chemistry and Metabolism of Lipids: Classification and biological functions. Fatty acids, their classification and distribution. Importance of polyunsaturated fatty acids. Chemistry of fish oil. Rancidity. Role of free radicals in lipid oxidation. Antioxidant. Lipoproteins. Fatty acid oxidation. Biosynthesis of fatty acids and cholesterol.	CLO1, CLO2 & CLO3	12
5	Chemistry and Metabolism of Nucleic acids: Composition, structural features and physicochemical functions. Replication, transcription and translation. Biological function of restriction enzymes. Concept of recombinant DNA and cloning.	CLO1, CLO2, CLO3 & CLO4	6
6	Enzymes: Classification. Elements of kinetics. Mode of action and inhibition. Coenzyme and prosthetic groups. Allosteric enzyme. Lysozymes. Enzyme immobilization.	CLO1, CLO2 & CLO3	4
7	Bioenergetics: Concept of free energy, entropy and enthalpy. Exergonic and endergonic reactions. ADP-ATP cycle. Bioluminescence.	CLO2	3
	Hormones: Characteristics and classification. Mode of action and biological functions of pituitary, hypothalamus, adrenal cortex and sex hormones.	CLO1 & CLO2	2
Total No. of Lectures			48

Teaching Strategy

Lecture
Group discussion
Exercise
Assignment
Video clip

Assessment Strategy

Multiple Choice Question
Short question
Essay type question
Assignment
Gap filling

Books Recommended:

Lehninger Principles of Biochemistry by David L. Nelson, 2008. 5^th W. H. freeman and company. New York.
Elliot, W.H. and Elliot, D.C. 1997. Biochemistry and Molecular Biology.
Textbook of Biochemistry by Thomas M. Devlin, 2002. 5^th John Wiley and Sons, Inc. Printed in USA
Biochemistry by Donald Voet, 1995. 2^nd edition, John Wiley and Sons, New York
Outlines of Biochemistry by Eric E. Conn and Paul K. Stumpf, 1987. 5^th John Wiley and Sons, New York
Biochemistry by Albert L Lehninger, 1982. 2^nd edition Kalyani Publishers. Ludhiana, New Delhi.
Harper’s Biochemistry by Robert K Murray, 2002. 25^th McGraw Hill. Printed in Singapore.
Biochemistry by Lubert Stryer, 1995. 4^th W. H. freeman and company. New York.
Watson, D. 1987. Molecular Biology of Gene. Bengamin, Inc.

----------------------------------------------------------------------------------------------------------------

Course Code: BMB 2206